Table 3 Difference in means of secondary endpoints between QD group and ADS group at 16-week

MMS

2.25 ± 0.51

2.53 ± 0.68

0.070

Partial Mayo score

0.03 ± 0.18

0.13 ± 0.35

0.155

MMES

1.23 ± 0.43

1.40 ± 0.50

0.128

 0 (%)

2 (6.25)

2 (6.67)

0.181

 1 (%)

23 (71.88)

15 (50.00)

 2 (%)

7 (21.88)

13 (43.33)

SIBDQ score

67.44 ± 2.34

64.10 ± 5.34

0.003^∗

Blood indicators

 CRP (mg/L)

8.19 ± 5.94

8.48 ± 4.42

0.893

 ESR (mm/h)

0.88 ± 0.93

0.95 ± 1.48

0.842

 Hb (g/L)

124.3 ± 8.92

119.2 ± 8.13

0.198

 ALB (g/L)

43.79 ± 3.58

42.03 ± 3.80

0.391