Fig. 6

CircFADS2 overexpression inhibited LPS-induced HBEpCs apoptosis via miR-133a. 1 × 106 HBEpCs were treated with 12 µg/ml LPS, and transfected with si-circFADS2, circFADS2 expression vector, miR-133a mimic or inhibitor. 48 h later, the apoptotic cells were detected by Annexin V-FITC Apoptosis detection assay (A). Cell viability was detected by MTT assay (B). The protein levels of cleaved caspase 3 and cleaved caspase 9 were detected by Western blot (C). *, p<0.05.