Fig. 5

AIM2 expression and localization in airway epithelial cells obtained from COPD patients and non-COPD non-smoker controls by upper airway brushing. a, b: Representative confocal images of AIM2 (red, Ab #1, aa250–300/354) and cleaved IL-1β (green) in cells from three different COPD patients (b) vs. three non-COPD non-smoker controls (a). Blue: DAPI. Scale bars in b are in micrometers and applied for the whole panel. C: Quantitation of bright AIM2 positive cells from COPD (n = 7) vs. non-COPD non-smoker control (n = 9)